Source: Sherman AL, Anderson JA, Rudolf CD, et al. Lactose-free milk or soy-based formulas do not improve caregivers’ distress or perceptions of difficult infant behavior. J Pediatr Gastroenterol Nutr. 2015;61(1):119-129; doi:10.197/0000000000000743. See AAP Grand Rounds commentary by Dr. Ronald Holmes (subscription required).
PICO Question: Among infants with feeding problems, do caregivers’ distress or perceptions of infant behaviors improve by feeding lactose-free milk-based or soy-based formula compared to milk-based, lactose-containing formula?
Question type: TreatmentStudy design: Double-blind randomized controlled