Source: Estes A, Munson J, Rogers SJ, et al. Long-term outcomes of early intervention in 6-year-old children with autism spectrum disorder. J Am Acad Chil Adolesc Psychiatry. 2015; 54(7): 580-587. doi:10.1016/j.jaac.2015.04.005. See AAP Grand Rounds commentary by Dr. Shelley Springer (subscription required).
PICO Question: Among children with autism who begin intensive early behavioral interventions at 18-30 months, do benefits persist at age 6 years?
Question type: Intervention
Study design: Randomized controlled trial